I reconstructed a structure to 3.X someish resolution, but notice the handness is wrong. So I inverted the handness and generate a new 3D. Then I import this inverted map as 3D refence and run "Auto Refine" with a new refinement package with 10 classes. Strangely, the resulting 3D map show the wrong handness again and totally not aligned with the orignal reference map. I am wondering where went wrong?